Swiss Rare Disease Registry offers PhD position (Screen4Care)

The Swiss Rare Disease Registry at the University of Berne is offering a funded PhD contract as part of the Screen4Care project, a public-private collaboration of 35 partners funded by the European Commission’s Innovative Medicines Initiative. Screen4Care aims to shorten the time required for rare disease diagnosis and efficient intervention by utilizing genetic newborn screening and advanced analysis methods such as machine learning.

Period: PhD contract (100%) for 3 years with a starting date no later than August 2022
Supervisors: Dr. Rowan Iskandar and Prof. med. Claudia Kuehni
Place of work: ISPM University of Bern and sitem-insel, Bern, Switzerland
Deadline for applying: February 15th, 2022

Under the supervision of Dr. Iskandar, the successful candidate will co-lead workstreams related to health economic evidence generation within Screen4Care. The PhD student will be mainly responsible for (1) the design and development of mathematical models to emulate the clinical pathways and disease trajectories, (2) the conduct of comparative analyses between genetic newborn screening and other screening modalities (e.g., cost-effectiveness analyses) that will be piggybacked to the envisioned clinical studies, and (3) the conduct of uncertainty quantification due to the pervasive uncertainty (e.g., lack of knowledge and data due to the rarity of the diseases). The candidate is expected to manage the daily activities of the workstreams and liaise with academic and industry partners.

For more information: